Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.53 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230924 | 0.99 | KMT2A (0.56) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL18779429 | 0.91 | KMT2A (0.58) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL18763562 | 0.89 | KMT2A (0.56) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL7941824 | 0.87 | KMT2A (0.62) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL6422578 | 0.86 | KMT2A (0.65) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL27946274 | 0.85 | VCAM1 (0.56) | KMT2AALDH1A1MAPTLMNAPOLB | |
| Hydrochloric Acid SCHEMBL11780689 | 0.85 | KMT2A (0.61) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL27923323 | 0.85 | VCAM1 (0.55) | KMT2AALDH1A1MAPTRAB9ACRHBP | |
| Piperidine SCHEMBL28288928 | 0.84 | KMT2A (0.43) | KMT2AALDH1A1MAPTRAB9ANPC1 | |
| Malonic Acid SCHEMBL28116103 | 0.84 | VCAM1 (0.51) | KMT2AALDH1A1MAPTNPC1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985405-B | Heterocyclic compounds and p27Kip1Decomposition inhibitor | ASKA制药株式会社 | 2016-07-06 | — | — | CN | disclosed |