SCHEMBL28066733

SCHEMBL28066733

CCCCCCc1ccc(CP(=O)(O)OP(=O)(OCC)OCC)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 1/20 0.63
S1PR1 P21453 13/20 0.50
S1PR3 Q99500 13/20 0.50
S1PR2 O95136 11/20 0.50
S1PR4 O95977 10/20 0.50
S1PR5 Q9H228 4/20 0.47
ESR1 P03372 2/20 0.46
ADRA2A P08913 2/20 0.46
ADORA3 P0DMS8 2/20 0.46
TACR2 P21452 2/20 0.46
SLC6A2 P23975 2/20 0.46
SLC6A4 P31645 2/20 0.46
SLC6A3 Q01959 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
SHBG P04278 1/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
HSPD1 P10809 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL914660 0.88 ENPP2 (0.60) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL28066732 0.87 S1PR1 (0.50) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL915295 0.84 ENPP2 (0.55) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL917185 0.84 ENPP2 (0.55) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL11028400 0.82 ENPP2 (0.71) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL915176 0.81 S1PR1 (0.54) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL11029748 0.81 ENPP2 (0.69) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL11026428 0.81 ENPP2 (0.69) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL11030041 0.81 ENPP2 (0.69) ENPP2S1PR1S1PR3S1PR2S1PR4
SCHEMBL915296 0.80 ENPP2 (0.51) ENPP2S1PR1S1PR3S1PR2S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102511089-B Novel organic semi-conductor material and use its electronic device RICOH CO.,LTD. (JP) 2016-06-01 CN disclosed