SCHEMBL28066834

SCHEMBL28066834

CCOP(=O)(Cc1ccc(CC)cc1)OCC.CCO[PH](=O)OCC

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
NPY5R Q15761 1/20 0.38
CYP2C19 P33261 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.35
CCNT1 O60563 2/20 0.35
CDK9 P50750 2/20 0.35
TLR8 Q9NR97 1/20 0.34
TLR7 Q9NYK1 1/20 0.34
HDAC1 Q13547 1/20 0.34
MAPT P10636 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
HTT P42858 1/20 0.32
SRC P12931 1/20 0.32
PTK2 Q05397 1/20 0.32
PLK1 P53350 1/20 0.32
IDO1 P14902 1/20 0.32
PPARD Q03181 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16062693 0.88 POLB (0.46) POLBNPY5RCYP2C19SMN1; SMN2TSHR
SCHEMBL28066786 0.85 NPY5R (0.43) POLBNPY5RCCNT1CDK9HDAC1
SCHEMBL28066775 0.83 ENPP2 (0.52)
SCHEMBL3375825 0.82 TSHR (0.50) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL479061 0.78 CCNT1 (0.46) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL2493713 0.77 TSHR (0.44) POLBNPY5RTSHRCCNT1CDK9
Hydrochloric Acid SCHEMBL3120206 0.76 CCNT1 (0.45) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL23822678 0.75 TSHR (0.43) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL25923558 0.75 TSHR (0.43) POLBNPY5RTSHRCCNT1CDK9
SCHEMBL915242 0.75 TSHR (0.43) POLBNPY5RTSHRCCNT1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102511089-B Novel organic semi-conductor material and use its electronic device RICOH CO.,LTD. (JP) 2016-06-01 CN disclosed