Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KLK7 | P49862 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395077 | 0.91 | TSHR (0.54) | TSHRPOLBCNR2ALDH1A1MAPK1 | |
| SCHEMBL28389994 | 0.90 | TSHR (0.53) | TSHRCNR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28392237 | 0.88 | TSHR (0.60) | TSHRCNR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL28393423 | 0.87 | TSHR (0.53) | TSHRPOLBCNR2ALDH1A1MAPK1 | |
| SCHEMBL28066986 | 0.86 | TSHR (0.58) | TSHRPOLBCNR2ALDH1A1MAPK1 | |
| SCHEMBL28389287 | 0.81 | TSHR (0.53) | TSHRCNR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL22293378 | 0.80 | TSHR (0.62) | TSHRPOLBCNR2ALDH1A1MAPK1 | |
| SCHEMBL28389293 | 0.80 | TSHR (0.67) | TSHRPOLBCNR2ALDH1A1MAPK1 | |
| SCHEMBL10580667 | 0.78 | TSHR (0.60) | TSHRPOLBCNR2ALDH1A1MAPK1 | |
| SCHEMBL28392029 | 0.78 | LMNA (0.49) | TSHRPOLBALDH1A1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778442-A | Olefin polymerization catalyst solid component, preparation method thereof, olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| CN-112759683-A | Olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-116135892-B | Method for preparing bimodal polyethylene resin for pipe material and bimodal polyethylene resin thereof | 中国石油化工股份有限公司 | 2024-10-15 | — | — | CN | disclosed |
| CN-111057169-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-111057168-B | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-111057168-A | Catalyst for olefin polymerization and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-04-24 | — | — | CN | disclosed |
| CN-103772536-B | A kind of catalytic component for vinyl polymerization or combined polymerization and catalyst thereof | SINOPEC CORP. (CN) | 2016-05-25 | — | — | CN | disclosed |