Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49966 | 0.98 | TDP1 (0.85) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11896258 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11896278 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL913237 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL7295237 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL9712789 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL10790013 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL6821603 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL14723101 | 0.96 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| Potassium SCHEMBL29767441 | 0.95 | TDP1 (0.79) | TDP1LMNAALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105596322-A | Tyrosinase inhibitor and applications thereof | LANHE (SHANGHAI) BIOTECHNOLOGY CO LTD | 2016-05-25 | — | — | CN | disclosed |