Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7295237 | 1.00 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11896278 | 1.00 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL10790013 | 1.00 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL11896258 | 1.00 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL14723101 | 1.00 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL9712789 | 1.00 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL6821603 | 1.00 | TDP1 (0.81) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL27972999 | 0.98 | TDP1 (0.79) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| Potassium SCHEMBL29767441 | 0.98 | TDP1 (0.79) | TDP1LMNAALDH1A1MAPK1HIF1A | |
| SCHEMBL49966 | 0.98 | TDP1 (0.85) | TDP1LMNAALDH1A1MAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12403116-B2 | Hydroxypentyl benzoic acid diester compound, and preparation method and pharmaceutical application thereof | CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUE OF MEDICINAL PLANT DEVELOPMENT (CN) | 2025-09-02 | — | — | US | disclosed |
| US-12403116-B2 | Hydroxypentyl benzoic acid diester compound, and preparation method and pharmaceutical application thereof | CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUE OF MEDICINAL PLANT DEVELOPMENT (CN) | 2025-09-02 | — | — | US | disclosed |
| US-12403116-B2 | Hydroxypentyl benzoic acid diester compound, and preparation method and pharmaceutical application thereof | CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUE OF MEDICINAL PLANT DEVELOPMENT (CN) | 2025-09-02 | — | — | US | disclosed |
| US-20250177342-A1 | HYDROXYPENTYL BENZOIC ACID DIESTER COMPOUND, AND PREPARATION METHOD AND PHARMACEUTICAL APPLICATION THEREOF | CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUTE OF MEDICINAL PLANT DEVELOPMENT (CN) | 2025-06-05 | — | — | US | disclosed |
| US-20250177342-A1 | HYDROXYPENTYL BENZOIC ACID DIESTER COMPOUND, AND PREPARATION METHOD AND PHARMACEUTICAL APPLICATION THEREOF | CHINESE ACADEMY OF MEDICAL SCIENCES INSTITUTE OF MEDICINAL PLANT DEVELOPMENT (CN) | 2025-06-05 | — | — | US | disclosed |
| EP-4342877-A1 | HYDROXYPENTYL BENZOIC ACID DIESTER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences (CN) | 2024-03-27 | — | — | EP | disclosed |
| EP-4342877-A1 | HYDROXYPENTYL BENZOIC ACID DIESTER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences (CN) | 2024-03-27 | — | — | EP | disclosed |
| WO-2023165094-A1 | HYDROXYPENTYL BENZOIC ACID DIESTER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国医学科学院药用植物研究所 | 2023-09-07 | — | — | WO | disclosed |
| CN-114315585-B | Hydroxypentyl benzoic acid diester compound, and preparation method and pharmaceutical application thereof | 中国医学科学院药用植物研究所 | 2022-05-13 | — | — | CN | disclosed |
| CN-114315585-B | Hydroxypentyl benzoic acid diester compound, and preparation method and pharmaceutical application thereof | 中国医学科学院药用植物研究所 | 2022-05-13 | — | — | CN | disclosed |
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5248810-A | Insecticides, acaricides | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-09-28 | — | — | US | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0169033-B1 | INHIBITORS OF SLOW REACTING SUBSTANCE OF ANAPHYLAXIS | SCHERING CORPORATION (US) | 1992-02-12 | — | — | EP | disclosed |
| EP-0432861-A1 | Halogenated olefines, process for the preparation thereof and their use as pesticides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-06-19 | — | — | EP | disclosed |
| EP-0169033-A2 | Inhibitors of slow reacting substance of anaphylaxis | SCHERING CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250177342-A1 | HYDROXYPENTYL BENZOIC ACID DIESTER COMPOUND, AND PREPARATION METHOD AND PHARMACEUTICAL APPLICATION THEREOF | GABRA6, GABRD, HCAR2 | TDP1 2705/4885LMNA 1451/4885ALDH1A1 957/4885 |
| US-12403116-B2 | Hydroxypentyl benzoic acid diester compound, and preparation method and pharmaceutical application thereof | GABRA6, GABRD, HCAR2 | TDP1 2705/4885LMNA 1451/4885ALDH1A1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.