SCHEMBL49966

SCHEMBL49966

O=C(OCCCCO)c1ccccc1

nearest known ligand 0.85

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.85
LMNA P02545 2/20 0.61
ALDH1A1 P00352 1/20 0.56
MAPK1 P28482 2/20 0.53
HIF1A Q16665 1/20 0.53
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.50
TSHR P16473 2/20 0.49
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
TP53 P04637 1/20 0.49
CYP3A4 P08684 1/20 0.49
F2 P00734 1/20 0.48
CNR2 P34972 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL913237 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL11896258 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL11896278 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL10790013 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL6821603 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL9712789 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL7295237 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL14723101 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
SCHEMBL28067101 0.98 TDP1 (0.81) TDP1LMNAALDH1A1MAPK1HIF1A
Potassium SCHEMBL29767441 0.96 TDP1 (0.79) TDP1LMNAALDH1A1MAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105001298-B A kind of synthesis isolation and purification method of indissoluble polypeptide 南京斯拜科生化实业有限公司 2018-01-02 CN claimed
US-8519085-B2 Coating compositions for containers and methods of coating VALSPAR SOURCING, INC. (US) 2013-08-27 US claimed
US-20120116048-A1 Coating Compositions for Containers and Methods of Coating VALSPAR SOURCING, INC. (US) 2012-05-10 US claimed
EP-1937434-A2 COATING COMPOSITIONS FOR CONTAINERS AND METHODS OF COATING Valspar Sourcing, Inc. (US) 2008-07-02 EP claimed
WO-2007048094-A2 COATING COMPOSITIONS FOR CONTAINERS AND METHODS OF COATING VALSPAR SOURCING, INC. (US) 2007-04-26 WO claimed
US-20070087146-A1 Coating Compositions for Containers and Methods of Coating VALSPAR SOURCING, INC. (US) 2007-04-19 US claimed
US-4656214-A DIESTERS EXXON RESEARCH & ENGINEERING CO. (US) 1987-04-07 US claimed
CN-119842650-A Acyltransferase for synthesizing polyester intermediate and application thereof 中国科学院天津工业生物技术研究所 2025-04-18 CN disclosed
US-20240360121-A1 GLS1 INHIBITORS FOR TREATING DISEASE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2024-10-31 US disclosed
US-11958849-B2 GLS1 inhibitors for treating disease BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-04-16 US disclosed
EP-1937434-B1 COATING COMPOSITIONS FOR CONTAINERS AND METHODS OF COATING SWIMC LLC (US) 2023-12-06 EP disclosed
US-20230242480-A1 Alkyne Compound, Vitamin D Compound, Analytical Method, and Production Method JEOL LTD. (JP) 2023-08-03 US disclosed
EP-3778809-B1 COATING COMPOSITIONS FOR CANS AND METHODS OF COATING SWIMC LLC (US) 2023-04-26 EP disclosed
US-4798842-A Inhibitors of slow reacting substance of anaphylaxis SCHERING CORPORATION (US) 1989-01-17 US disclosed
US-4758594-A Inhibitors of slow reacting substance of anaphylaxis SCHERING CORPORATION (US) 1988-07-19 US disclosed
US-4696946-A Topical Treatment of hyperproliferative skin diseases SCHERING CORPORATION (US) 1987-09-29 US disclosed
EP-0169033-A2 Inhibitors of slow reacting substance of anaphylaxis SCHERING CORPORATION (US) 1986-01-22 EP disclosed
EP-0146880-A2 Copolyester-carbonate resins exhibiting improved processability GENERAL ELECTRIC COMPANY (US) 1985-07-03 EP disclosed
US-4487917-A ENGINEERING THERMOPLASTICS GENERAL ELECTRIC COMPANY (US) 1984-12-11 US disclosed
US-4017524-A PRINTING AND DYEING OF SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360121-A1 GLS1 INHIBITORS FOR TREATING DISEASE GLS2, GLS, GLG1 TDP1 2403/4885LMNA 3276/4885ALDH1A1 882/4885
US-11958849-B2 GLS1 inhibitors for treating disease GLS2, GLS, GLG1 TDP1 2403/4885LMNA 3276/4885ALDH1A1 882/4885
US-20230242480-A1 Alkyne Compound, Vitamin D Compound, Analytical Method, and Production Method VDR, CYP2R1, CYP24A1 TDP1 4878/4885LMNA 1250/4885ALDH1A1 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.