SCHEMBL28067241

SCHEMBL28067241

O=C(Cc1ccccc1)Cc1ccc2ccccc2c1O

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.50
CYP1B1 Q16678 1/20 0.50
CFTR P13569 1/20 0.49
LDHA P00338 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4889688 0.83 TDP1 (0.65) LDHA
SCHEMBL3239922 0.81 TDP1 (0.68)
SCHEMBL28538435 0.78
SCHEMBL664782 0.78
Hydrochloric Acid SCHEMBL27690655 0.76 CES1 (0.67)
Succinic Acid SCHEMBL9658515 0.76
SCHEMBL9220181 0.76 CYP1A1 (0.55) CYP1A1CYP1B1
SCHEMBL29714011 0.76 CYP1A1 (0.55) CYP1A1CYP1B1
SCHEMBL11460264 0.74 L3MBTL1 (0.48)
SCHEMBL77563 0.74 CES1 (0.70)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732339-B Dapoxetine hydrochloride intermediate and preparation method thereof 上海医药工业研究院 2019-06-04 CN disclosed
CN-105732339-A Dapoxetine intermediate and preparation method thereof 上海医药工业研究院 2016-07-06 CN disclosed