⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4889688 | 0.84 | TDP1 (0.65) | — | |
| SCHEMBL11460264 | 0.81 | L3MBTL1 (0.48) | — | |
| SCHEMBL2167788 | 0.81 | — | — | |
| SCHEMBL29886792 | 0.81 | — | — | |
| SCHEMBL8474945 | 0.81 | POLB (0.47) | — | |
| SCHEMBL266575 | 0.79 | TDP1 (0.69) | — | |
| SCHEMBL30716622 | 0.79 | TDP1 (0.69) | — | |
| SCHEMBL29527363 | 0.79 | — | — | |
| SCHEMBL28145097 | 0.79 | KDM4E (0.50) | — | |
| SCHEMBL28067241 | 0.78 | CYP1A1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112479998-B | Dihydroquinoline fluorescent probe and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2022-03-15 | — | — | CN | disclosed |
| CN-112479998-A | Dihydroquinoline fluorescent probe and preparation method and application thereof | 广州中医药大学(广州中医药研究院) | 2021-03-12 | — | — | CN | disclosed |