Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765637 | 0.81 | MAPT (0.48) | IDO1NPC1GAAMAPTRAB9A | |
| SCHEMBL17295620 | 0.80 | IDO1 (0.44) | IDO1NPC1GAAMAPTMAPK1 | |
| SCHEMBL16664764 | 0.80 | IDO1 (0.44) | IDO1NPC1GAAMAPTMAPK1 | |
| SCHEMBL28067323 | 0.76 | NMT1 (0.43) | MAPTFYN | |
| SCHEMBL10958055 | 0.75 | KMO (0.50) | — | |
| SCHEMBL9389147 | 0.74 | KMT2A (0.60) | IDO1NPC1GAAMAPTMAPK1 | |
| SCHEMBL17948716 | 0.72 | MMP2 (0.42) | IDO1MAPTPTGS2FYN | |
| SCHEMBL10960418 | 0.72 | CA12 (0.47) | F2RL3 | |
| SCHEMBL23539461 | 0.69 | CYP2E1 (0.56) | IDO1NPC1MAPTRAB9AF2RL3 | |
| SCHEMBL30042352 | 0.69 | CYP2E1 (0.56) | IDO1NPC1MAPTRAB9AF2RL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153999-B | Compounds as cannabinoid receptor-1 inhibitors | AMOREPACIFIC CORP. (KR) | 2016-06-01 | — | — | CN | disclosed |