Tricyclazole

Tricyclazole

SCHEMBL28067349

Cc1cccc2sc3nncn3c12.N

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BRPF1 P55201 1/20 0.97
TNKS2 Q9H2K2 17/20 0.64
PARP2 Q9UGN5 16/20 0.64
PARP15 Q460N3 16/20 0.64
PARP10 Q53GL7 14/20 0.64
PARP14 Q460N5 2/20 0.49
TNKS O95271 1/20 0.42
PARP1 P09874 1/20 0.42
PARP11 Q9NR21 1/20 0.42
PARP4 Q9UKK3 1/20 0.42
PARP3 Q9Y6F1 1/20 0.42
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tricyclazole SCHEMBL23082 0.98 BRPF1 (1.00) BRPF1TNKS2PARP2PARP15PARP10
Tricyclazole SCHEMBL14721539 0.98 BRPF1 (1.00) BRPF1TNKS2PARP2PARP15PARP10
Tricyclazole SCHEMBL28326365 0.81 BRPF1 (0.68) BRPF1TNKS2PARP2PARP15PARP10
SCHEMBL11743096 0.79 BRPF1 (0.67) BRPF1TNKS2PARP2PARP15PARP10
SCHEMBL11746004 0.79 BRPF1 (0.67) BRPF1TNKS2PARP2PARP15PARP10
SCHEMBL11746277 0.79 BRPF1 (0.67) BRPF1TNKS2PARP2PARP15PARP10
Tricyclazole SCHEMBL28234325 0.79 BRPF1 (0.64) BRPF1TNKS2PARP2PARP15PARP10
SCHEMBL11744684 0.78 BRPF1 (0.66) BRPF1TNKS2PARP2PARP15PARP10
SCHEMBL11743573 0.78 TNKS2 (1.00) BRPF1TNKS2PARP2PARP15PARP10
SCHEMBL11745019 0.78 BRPF1 (0.66) BRPF1TNKS2PARP2PARP15PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105828608-A Pesticidal Compositions And Related Methods 美国陶氏益农公司 2016-08-03 CN claimed
CN-105828610-A Pesticidal compositions and methods related thereto 美国陶氏益农公司 2016-08-03 CN claimed
CN-105753839-A Pesticidal Compositions And Processes Related Thereto 陶氏益农公司 2016-07-13 CN claimed
CN-105732580-A Pesticidal compositions and methods related thereto 陶氏益农公司 2016-07-06 CN claimed
CN-105732579-A Pesticidal compositions and methods related thereto 陶氏益农公司 2016-07-06 CN claimed
CN-105753839-A Pesticidal Compositions And Processes Related Thereto 陶氏益农公司 2016-07-13 CN disclosed
CN-105732579-A Pesticidal compositions and methods related thereto 陶氏益农公司 2016-07-06 CN disclosed
CN-105732580-A Pesticidal compositions and methods related thereto 陶氏益农公司 2016-07-06 CN disclosed