Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800806 | 0.80 | CA1 (0.38) | — | |
| SCHEMBL8111516 | 0.79 | ELANE (0.31) | — | |
| SCHEMBL28229786 | 0.77 | ALOX15 (0.50) | — | |
| SCHEMBL1371292 | 0.77 | RAB9A (0.42) | — | |
| SCHEMBL29040538 | 0.76 | RAB9A (0.41) | — | |
| SCHEMBL27720748 | 0.75 | PTGS1 (0.38) | MRGPRX4 | |
| SCHEMBL330747 | 0.73 | ORAI1 (0.46) | — | |
| SCHEMBL27957983 | 0.72 | CYP11B1 (0.36) | — | |
| SCHEMBL1973121 | 0.72 | ESR2 (0.39) | — | |
| SCHEMBL21805853 | 0.71 | ORAI1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105228982-B | 3-acetylamino-1- (phenyl-heteroaryl-aminocarbonyl or phenyl-heteroaryl-carbonylamino) benzene derivatives for the treatment of hyperproliferative disorders | 拜耳制药股份公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-106995415-A | It is used as the fusion benzo oxygen azepine * ketone of ion channel modulators | 吉利德科学公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-103857659-B | Fused benzoxazepines as modulators of ion channels | 吉利德科学公司 | 2017-02-15 | — | — | CN | disclosed |
| CN-103153999-B | Compounds as cannabinoid receptor-1 inhibitors | AMOREPACIFIC CORP. (KR) | 2016-06-01 | — | — | CN | disclosed |