SCHEMBL28067477

SCHEMBL28067477

FC1=C(F)C(c2ccc3ccccc3c2)c2c(F)c(F)c(F)c(F)c21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 5/20 0.36
SLC6A2 P23975 3/20 0.36
SLC6A3 Q01959 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
KDM4E B2RXH2 1/20 0.35
KDM1A O60341 2/20 0.34
RCOR1 Q9UKL0 1/20 0.34
EGFR P00533 3/20 0.33
ERBB2 P04626 3/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP2D6 P10635 1/20 0.32
KCNH2 Q12809 1/20 0.32
MAOB P27338 1/20 0.31
GSK3B P49841 1/20 0.31
ADK P55263 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277911 0.79 IDO1 (0.43) HTR2CHTR2BKDM1A
SCHEMBL28067464 0.72 KDM1A (0.40) SLC6A4SLC6A2SLC6A3KDM4EKDM1A
SCHEMBL6280785 0.66 HTR2C (0.38) HTR2CHTR2BKDM1A
SCHEMBL6280695 0.65 HTR2A (0.37) HTR2CHTR2BKDM1AALDH1A1
SCHEMBL4154803 0.64 CYP1A2 (0.50) CYP1A2CYP2A6KDM4EALDH1A1CYP3A4
SCHEMBL6281007 0.62
SCHEMBL1542951 0.61 MAPT (0.47) SLC6A4SLC6A2SLC6A3HTR2CHTR2B
SCHEMBL28932548 0.61 MAOA (0.44) SLC6A4SLC6A2SLC6A3HTR2CHTR2B
SCHEMBL28559262 0.60 KDM4E (0.46) SLC6A4SLC6A2SLC6A3CYP1A2CYP2A6
SCHEMBL13617411 0.60 MAPT (0.57) CYP1A2HTR2BKDM4EALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105531327-A Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORP 2016-04-27 CN disclosed