SCHEMBL28067464

SCHEMBL28067464

FC1=C(F)C(c2cccc3ccccc23)c2c(F)c(F)c(F)c(F)c21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.40
SLC6A4 P31645 4/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A3 Q01959 2/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
RCE1 Q9Y256 1/20 0.34
EGFR P00533 3/20 0.33
ERBB2 P04626 3/20 0.33
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
KEAP1 Q14145 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MTNR1A P48039 1/20 0.32
IDO1 P14902 1/20 0.32
MAPT P10636 3/20 0.31
KDM4E B2RXH2 2/20 0.31
TDP2 O95551 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280785 0.79 HTR2C (0.38) KDM1A
SCHEMBL6280695 0.71 HTR2A (0.37) KDM1AALDH1A1HPGDMAPT
SCHEMBL6281007 0.66
SCHEMBL6675754 0.64 KDM1A (0.53) KDM1ASLC6A4SLC6A2SLC6A3MEN1
SCHEMBL4138564 0.64 DHFR (0.44) ALDH1A1HPGDCYP3A4TSHRKEAP1
SCHEMBL7180602 0.62
SCHEMBL6277911 0.62 IDO1 (0.43) KDM1AIDO1
SCHEMBL416279 0.60 CYP1A2 (0.53) KDM1AALDH1A1NPSR1
SCHEMBL7070565 0.60 CYP2A6 (0.50) KDM1ASLC6A4SLC6A2SLC6A3MEN1
SCHEMBL668166 0.60 CYP2C9 (0.49) KDM1ASLC6A4SLC6A2SLC6A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105531327-A Curable coloring composition, cured film, color filter, method for manufacturing color filter, solid-state image pickup element, picture display device, and triarylmethane compound FUJIFILM CORP 2016-04-27 CN disclosed