SCHEMBL28067626

SCHEMBL28067626

Nc1ccc(-c2ccccc2)c(C=Cc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.53
MAOA P21397 4/20 0.53
MAOB P27338 4/20 0.53
PELI1 Q96FA3 1/20 0.41
BACE1 P56817 1/20 0.41
PTPN1 P18031 1/20 0.41
PTPN6 P29350 1/20 0.41
TRPA1 O75762 1/20 0.40
NFE2L2 Q16236 1/20 0.40
KMT2A Q03164 2/20 0.40
ATM Q13315 1/20 0.40
TLR9 Q9NR96 1/20 0.40
NPC1 O15118 1/20 0.40
MAPT P10636 1/20 0.40
GFER P55789 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5337729 0.95 CYP19A1 (0.57) CYP19A1MAOAMAOBPELI1BACE1
SCHEMBL5337738 0.95 CYP19A1 (0.57) CYP19A1MAOAMAOBPELI1BACE1
SCHEMBL3972610 0.83 MAOA (0.49) CYP19A1MAOAMAOBPELI1BACE1
SCHEMBL29713155 0.81 PELI1 (0.53) CYP19A1MAOAMAOBPELI1BACE1
SCHEMBL16738162 0.81 PELI1 (0.53) CYP19A1MAOAMAOBPELI1BACE1
SCHEMBL16738163 0.81 PELI1 (0.53) CYP19A1MAOAMAOBPELI1BACE1
SCHEMBL2786941 0.80 CYP19A1 (0.61) CYP19A1MAOAMAOBPELI1BACE1
SCHEMBL6303896 0.79 CYP19A1 (0.59) CYP19A1MAOAMAOBTRPA1NFE2L2
SCHEMBL6303895 0.79 CYP19A1 (0.59) CYP19A1MAOAMAOBTRPA1NFE2L2
SCHEMBL31168864 0.78 CYP19A1 (0.53) CYP19A1MAOAMAOBPELI1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105612628-A Charge-transporting varnish NISSAN CHEMICAL IND LTD 2016-05-25 CN disclosed