Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.57 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337729 | 1.00 | CYP19A1 (0.57) | CYP19A1MAOAMAOBCYP3A4TAAR1 | |
| SCHEMBL28067626 | 0.95 | CYP19A1 (0.53) | CYP19A1MAOAMAOBCYP3A4TAAR1 | |
| SCHEMBL2786941 | 0.86 | CYP19A1 (0.61) | CYP19A1MAOAMAOBCYP3A4TAAR1 | |
| SCHEMBL27538754 | 0.81 | CYP19A1 (0.55) | CYP19A1MAOAMAOBCYP3A4TAAR1 | |
| SCHEMBL27867207 | 0.80 | CYP19A1 (0.53) | CYP19A1MAOAMAOBCYP3A4TAAR1 | |
| SCHEMBL31168864 | 0.80 | CYP19A1 (0.53) | CYP19A1MAOAMAOBCYP3A4TAAR1 | |
| SCHEMBL6303896 | 0.78 | CYP19A1 (0.59) | CYP19A1MAOAMAOBCYP1B1TRPA1 | |
| SCHEMBL3972610 | 0.78 | MAOA (0.49) | CYP19A1MAOAMAOBCYP1B1TRPA1 | |
| SCHEMBL6303895 | 0.78 | CYP19A1 (0.59) | CYP19A1MAOAMAOBCYP1B1TRPA1 | |
| SCHEMBL14160333 | 0.77 | CYP19A1 (0.86) | CYP19A1MAOAMAOBCYP3A4TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007210950-A | STYRYLBENZIDINE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR | KYOCERA MITA CORP | 2007-08-23 | — | — | JP | disclosed |