Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 6/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 6/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.46 |
| ▸ | KDM5C | P41229 | 5/20 | 0.46 |
| ▸ | KDM6B | O15054 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL3455209 | 0.90 | GLRA1 (0.56) | TSHRKDM4ELMNAGABRR1PHF8 | |
| Beta-Alanine SCHEMBL27907224 | 0.89 | KDM4E (0.52) | TSHRKDM4ELMNAGABRR1PHF8 | |
| Glycine SCHEMBL28475068 | 0.87 | KDM4E (0.54) | TSHRKDM4ELMNAGABRR1EGLN1 | |
| Bicarbonate SCHEMBL27949760 | 0.87 | MGAM (0.52) | TSHRKDM4ELMNAMGAMGAA | |
| SCHEMBL12140935 | 0.87 | — | — | |
| SCHEMBL2148 | 0.87 | — | — | |
| SCHEMBL13169650 | 0.87 | — | — | |
| Acetic Acid SCHEMBL7017383 | 0.84 | MGAM (0.57) | TSHRKDM4ELMNAPHF8KDM2A | |
| Acetic Acid SCHEMBL19468 | 0.84 | MGAM (0.57) | TSHRKDM4ELMNAPHF8KDM2A | |
| Oxalic Acid SCHEMBL30540157 | 0.84 | LMNA (0.50) | TSHRKDM4ELMNAMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481977-A | Glycocholic-acid immunodetection reagent based on anti-glycocholic acid specific antibody and preparation method thereof | BEIJING HUAXINYUAN BIOTECHNOLOGY CO LTD | 2016-04-13 | — | — | CN | disclosed |