Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13141189 | 0.79 | GAA (0.62) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL6763499 | 0.79 | GAA (0.58) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL6767882 | 0.76 | GAA (0.54) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL13303940 | 0.75 | GAA (0.68) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL6767005 | 0.73 | GAA (0.51) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL18235086 | 0.72 | MAPT (0.38) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL11392894 | 0.72 | CA2 (0.39) | KMT2AMEN1 | |
| SCHEMBL3818109 | 0.72 | GAA (0.63) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL9619832 | 0.72 | GAA (0.63) | GAAPKMKDM4EALDH1A1MAPT | |
| SCHEMBL7597403 | 0.72 | GAA (0.63) | GAAPKMKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622580-A | Benzoimidazoles as prolyl hydroxylase inhibitors | JANSSEN PHARMACEUTICA NV | 2016-06-01 | — | — | CN | disclosed |