Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6767005 | 0.87 | GAA (0.51) | GAAPKMALDH1A1MAPTESR2 | |
| SCHEMBL6766396 | 0.83 | GAA (0.51) | GAAPKMALDH1A1MAPTESR2 | |
| SCHEMBL6763499 | 0.82 | GAA (0.58) | GAAPKMALDH1A1MAPTKMT2A | |
| SCHEMBL2056376 | 0.80 | GAA (0.63) | GAAPKMALDH1A1MAPTKMT2A | |
| SCHEMBL13141189 | 0.79 | GAA (0.62) | GAAPKMALDH1A1MAPTKMT2A | |
| SCHEMBL5393113 | 0.77 | GAA (0.59) | GAAPKMALDH1A1MAPTKMT2A | |
| SCHEMBL28067705 | 0.76 | GAA (0.54) | GAAPKMALDH1A1MAPTKMT2A | |
| SCHEMBL13303940 | 0.75 | GAA (0.68) | GAAPKMALDH1A1MAPTKMT2A | |
| SCHEMBL6763567 | 0.74 | SMN1; SMN2 (0.54) | GAAPKMALDH1A1MAPTHSD17B10 | |
| SCHEMBL6763601 | 0.73 | GAA (0.47) | GAAPKMALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699880-B1 | STIMULATE MUSCARINIC ACETYLCHOLINE RECEPTORS M4, ANALGESICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-03-02 | — | — | US | disclosed |
| EP-1221443-A1 | SUBSTITUTED IMIDAZOLIDINONE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |