Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | HSD11B2 | P80365 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232571 | 0.84 | HSD11B1 (0.57) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL230322 | 0.84 | HSD11B1 (0.57) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL12308304 | 0.83 | HSD11B1 (0.60) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL6325458 | 0.81 | HSD11B1 (0.57) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL12334440 | 0.75 | HSD11B1 (0.56) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL257525 | 0.75 | HSD11B1 (0.56) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL231998 | 0.74 | HSD11B1 (0.70) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL17350282 | 0.73 | HSD11B1 (0.54) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL3041989 | 0.73 | HSD11B1 (0.54) | HSD11B1EPHX2HSD11B2 | |
| SCHEMBL14697322 | 0.73 | HSD11B1 (0.54) | HSD11B1EPHX2HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242192-B | The inhibitor of 11-beta-hydroxysteroid dehydrogenase 1 type enzyme | ABBVIE INC. (US) | 2016-05-04 | — | — | CN | disclosed |