Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RARB | P10826 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9864149 | 0.85 | SLC6A2 (0.52) | IDO1ACACBTSHRTP53RAB9A | |
| SCHEMBL24897860 | 0.82 | ACACB (0.38) | ACACBLMNATSHRL3MBTL1TP53 | |
| SCHEMBL3007047 | 0.82 | MME (0.41) | ACACBTSHREPHX1TP53NPC1 | |
| SCHEMBL13886151 | 0.82 | ACACB (0.38) | IDO1ACACBTSHRTP53MEN1 | |
| SCHEMBL15012373 | 0.81 | TRPA1 (0.47) | IDO1LMNATSHRTP53HPGD | |
| SCHEMBL6714539 | 0.81 | IDO1 (0.41) | TYRIDO1ACACBPTGS1PTGS2 | |
| SCHEMBL7354997 | 0.80 | TAAR1 (0.53) | EPHX1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25209356 | 0.80 | TAAR1 (0.53) | EPHX1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24897743 | 0.78 | ALDH1A1 (0.39) | TYRLMNATSHRL3MBTL1TP53 | |
| SCHEMBL1069669 | 0.78 | SLC6A4 (0.55) | IDO1ACACBTSHRL3MBTL1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666504-B | Compounds as lysophosphatidic acid receptor antagonists | AMIRA PHARMACEUTICALS, INC. (US) | 2016-06-01 | — | — | CN | disclosed |