SCHEMBL28067904

SCHEMBL28067904

COC(=O)c1ccc(C)c(C(=O)O)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA7 P43166 2/20 0.42
CA9 Q16790 2/20 0.42
CA14 Q9ULX7 2/20 0.42
PDK2 Q15119 1/20 0.42
PDK4 Q16654 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.40
LMNA P02545 1/20 0.40
KDM4E B2RXH2 6/20 0.40
ALDH1A1 P00352 4/20 0.40
GAA P10253 3/20 0.40
HSD17B10 Q99714 3/20 0.40
GLA P06280 2/20 0.40
MAPT P10636 2/20 0.40
ATM Q13315 2/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13199184 0.89 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL15957674 0.85 KDM4E (0.42) CA12CA1CA2CA7CA9
SCHEMBL3969049 0.85 CA12 (0.42) CA12CA1CA2CA7CA9
SCHEMBL28139096 0.85 LMNA (0.42) CA12CA1CA2CA7CA9
SCHEMBL14059057 0.84 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL27169657 0.84 ALDH1A1 (0.35) CA12CA1CA2CA7CA9
SCHEMBL27464602 0.83 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL19307715 0.82 NPC1 (0.41) CA12CA1CA2CA7CA9
SCHEMBL9305593 0.82 ALDH1A1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL195882 0.82 CYP1A2 (0.44) MEN1KMT2ATSHRLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105916939-B Poly (phenylene ether) composition and article 沙特基础工业全球技术有限公司 2018-02-02 CN disclosed
CN-104736637-B Poly (phenylene ether) composition and article 沙特基础全球技术有限公司 2018-01-30 CN disclosed
CN-107109008-A Flame-proofed polystyrene composition SABIC环球技术有限责任公司 2017-08-29 CN disclosed
CN-105392840-B Mechanograph and the composition used in its manufacture 沙特基础全球技术有限公司 2017-08-25 CN disclosed
CN-107075249-A Poly- (phenylene ether) composition of fire retardant, enhanced polyamide 沙特基础工业全球技术有限公司 2017-08-18 CN disclosed
CN-107001788-A Transparent poly- (phenylene ether) composition, their manufacture method and the food package film and container by its acquisition 沙特基础工业全球技术有限公司 2017-08-01 CN disclosed
CN-105164205-B Poly- (phenylene ether) composition and product 沙特基础全球技术有限公司 2017-07-28 CN disclosed
CN-106867242-A Semi-aromatic nylon and Polyphenyl ether alloy material and its preparation method and application 上海杰事杰新材料(集团)股份有限公司 2017-06-20 CN disclosed
CN-104245841-B Poly- (phenylene ether) composition, product and method 沙特基础全球技术有限公司 2017-05-31 CN disclosed
CN-104755536-B poly (phenylene ether) articles and compositions 沙特基础全球技术有限公司 2017-04-26 CN disclosed
CN-103748169-B Poly (arylene ether) composition, method and product 沙特基础全球技术有限公司 2017-03-08 CN disclosed
CN-104662089-B Poly(phenylene ether) composition and article 沙特基础全球技术有限公司 2017-02-22 CN disclosed
CN-106433086-A Flame-retardant polyphenylene ether resin composition having high rigidity and high impact strength 现代自动车株式会社 2017-02-22 CN disclosed
CN-106414606-A Poly(phenylene ether) composition and article 沙特基础工业全球技术有限公司 2017-02-15 CN disclosed
CN-104955873-B Triblock copolymer, its forming method and comprise its increase-volume compositions 沙特基础全球技术有限公司 2016-10-19 CN disclosed
CN-105916939-A Poly (phenylene ether) composition and article 沙特基础工业全球技术有限公司 2016-08-31 CN disclosed
CN-104432484-B A kind of tobacco leaf processing method CHINA TOBACCO GUIZHOU INDUSTRIAL CO. LTD. (CN) 2016-05-04 CN disclosed