Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 10/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068085 | 0.78 | HTR2A (0.40) | HTR2AHTR6NFE2L2GRM5 | |
| SCHEMBL28047883 | 0.75 | SNCA (0.41) | HTR2CHTR2B | |
| SCHEMBL29953488 | 0.74 | CCNT1 (0.38) | — | |
| SCHEMBL2198627 | 0.71 | HTR2A (0.60) | HTR2AHTR6NFE2L2GRM5KCNH2 | |
| SCHEMBL19327019 | 0.70 | HTR2A (0.62) | HTR2AHTR6NFE2L2GRM5KCNH2 | |
| SCHEMBL28068066 | 0.69 | KMT2A (0.41) | HTR2AHTR6NFE2L2HTR2CHTR2B | |
| SCHEMBL775608 | 0.69 | HTR2C (0.59) | HTR2AHTR6NFE2L2KCNH2HTR2C | |
| SCHEMBL2198404 | 0.69 | HTR2A (0.60) | HTR2AHTR6NFE2L2GRM5KCNH2 | |
| SCHEMBL3208018 | 0.69 | HTR2A (0.60) | HTR2AHTR6NFE2L2GRM5KCNH2 | |
| SCHEMBL4233311 | 0.68 | HTR2A (0.45) | HTR2AHTR6NFE2L2GRM5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |