Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068048 | 0.78 | HTR2A (0.46) | HTR2ANFE2L2GRM5HTR6 | |
| SCHEMBL28068066 | 0.78 | KMT2A (0.41) | HTR2ANFE2L2HTR6 | |
| SCHEMBL29950684 | 0.72 | CCNT1 (0.49) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL15331451 | 0.68 | CYP2A6 (0.53) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL28068053 | 0.68 | CCNT1 (0.49) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL29935646 | 0.68 | TDO2 (0.64) | CYP2A6IMPDH2TDO2IDO1 | |
| SCHEMBL187434 | 0.68 | TDO2 (0.64) | CYP2A6IMPDH2TDO2IDO1 | |
| SCHEMBL29950941 | 0.67 | CCNT1 (0.44) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL3098278 | 0.67 | HTR2A (0.44) | HTR2ANFE2L2HTR6 | |
| SCHEMBL28068102 | 0.67 | HTR6 (0.45) | CYP2A6IMPDH2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |