Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.38 |
| ▸ | HTR6 | P50406 | 10/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068085 | 0.78 | HTR2A (0.40) | NFE2L2HTR6HTR2A | |
| SCHEMBL3098278 | 0.70 | HTR2A (0.44) | NFE2L2HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL28068048 | 0.69 | HTR2A (0.46) | NFE2L2HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL29955200 | 0.67 | KMT2A (0.49) | KMT2A | |
| SCHEMBL16494923 | 0.67 | NFE2L2 (0.47) | NFE2L2HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL775608 | 0.66 | HTR2C (0.59) | KMT2ANFE2L2HTR6HTR2AHTR2C | |
| SCHEMBL5263827 | 0.65 | KMT2A (0.54) | KMT2A | |
| SCHEMBL27470883 | 0.65 | NFE2L2 (0.60) | NFE2L2HTR6HTR2AHTR2CHTR2B | |
| SCHEMBL27585408 | 0.65 | AKR1B1 (0.69) | — | |
| SCHEMBL4563072 | 0.64 | HDAC1 (0.46) | NFE2L2HTR6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |