Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28829310 | 0.82 | HTR6 (0.45) | HTR6AKR1B1CA1CA2MMP1 | |
| SCHEMBL28068118 | 0.81 | HTR6 (0.45) | HTR6AKR1B1ALDH1A1CA1CA2 | |
| SCHEMBL2533000 | 0.80 | CYP2A6 (0.58) | CYP2A6IMPDH2KDM4EALDH1A1MAPT | |
| SCHEMBL29644219 | 0.80 | CYP2A6 (0.58) | CYP2A6IMPDH2KDM4EALDH1A1MAPT | |
| SCHEMBL28068053 | 0.77 | CCNT1 (0.49) | HTR6CYP2A6IMPDH2KDM4EALDH1A1 | |
| SCHEMBL30859041 | 0.75 | CA1 (0.65) | HTR6AKR1B1CA1CA2MMP1 | |
| SCHEMBL8863056 | 0.75 | CA1 (0.65) | HTR6AKR1B1CA1CA2MMP1 | |
| Hydrochloric Acid SCHEMBL11261755 | 0.73 | CA1 (0.62) | HTR6AKR1B1CA1CA2MMP1 | |
| SCHEMBL8685220 | 0.73 | AKR1B1 (0.43) | HTR6AKR1B1MAPTCA1CA2 | |
| SCHEMBL28207032 | 0.73 | ESR1 (0.54) | HTR6AKR1B1CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |