Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.49 |
| ▸ | CDK9 | P50750 | 1/20 | 0.49 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 4/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068102 | 0.77 | HTR6 (0.45) | CYP2A6IMPDH2ALDH1A1KDM4EMAPT | |
| SCHEMBL29957979 | 0.76 | CCNT1 (0.57) | CCNT1CDK9HASPINTDO2IDO1 | |
| SCHEMBL28068101 | 0.75 | NR4A2 (0.56) | HTR6NAMPT | |
| SCHEMBL2535321 | 0.73 | ALDH1A1 (0.54) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL31404866 | 0.71 | NAPRT (0.68) | CYP2A6ALDH1A1KDM4EKMT2AHTR6 | |
| SCHEMBL9232776 | 0.71 | NAPRT (0.68) | CYP2A6ALDH1A1KDM4EKMT2AHTR6 | |
| SCHEMBL31129989 | 0.70 | CYP2A6 (0.53) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL6015636 | 0.70 | CYP2A6 (0.53) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL29664462 | 0.70 | CCNT1 (0.62) | CCNT1CDK9HASPINCYP2A6IMPDH2 | |
| SCHEMBL2268299 | 0.70 | CCNT1 (0.62) | CCNT1CDK9HASPINCYP2A6IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-B | Sulfonylindole derivatives and process for producing the same | 株式会社大熊制药 | 2018-04-10 | — | — | CN | disclosed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |