Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | HTR1F | P30939 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28068041 | 0.99 | HTR6 (0.45) | HTR6KEAP1NFE2L2CHRNB4CHRNA3 | |
| SCHEMBL16626404 | 0.91 | HTR6 (0.45) | HTR6DRD2HTR7HTR1AHTR1D | |
| SCHEMBL28068045 | 0.90 | HTR6 (0.42) | HTR6CHRNB4CHRNA3CYP11B1CYP11B2 | |
| SCHEMBL17971581 | 0.90 | HTR6 (0.44) | HTR6DRD2HTR7HTR1AHTR1D | |
| SCHEMBL16626627 | 0.90 | HTR6 (0.46) | HTR6KEAP1NFE2L2CHRNB4CHRNA3 | |
| SCHEMBL16626785 | 0.90 | HTR6 (0.44) | HTR6CYP11B1CYP11B2DRD2HTR7 | |
| Hydrochloric Acid SCHEMBL16618778 | 0.90 | HTR6 (0.44) | HTR6DRD2HTR7HTR1AHTR1D | |
| SCHEMBL17971576 | 0.90 | PDE4A (0.42) | HTR6 | |
| SCHEMBL16626784 | 0.89 | HTR6 (0.42) | HTR6CYP11B1CYP11B2 | |
| SCHEMBL28829305 | 0.89 | HTR6 (0.43) | HTR6KEAP1NFE2L2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |