Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | IDE | P14735 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068112 | 0.90 | HTR6 (0.46) | HTR6CHRNB4CHRNA3CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL28068041 | 0.90 | HTR6 (0.45) | HTR6CHRNB4CHRNA3CYP11B1CYP11B2 | |
| SCHEMBL28068056 | 0.89 | IDE (0.42) | HTR6CHRNB4CHRNA3NAMPTIDE | |
| SCHEMBL28068051 | 0.88 | IDE (0.41) | HTR6CHRNB4CHRNA3NAMPTIDE | |
| SCHEMBL28068083 | 0.85 | IDE (0.43) | HTR6CHRNB4CHRNA3NAMPTIDE | |
| SCHEMBL28068087 | 0.84 | KMT2A (0.49) | HTR6CHRNB4CHRNA3LMNACYP11B1 | |
| SCHEMBL28068091 | 0.83 | HTR6 (0.42) | HTR6CHRNB4CHRNA3IDEPPARG | |
| SCHEMBL17971581 | 0.81 | HTR6 (0.44) | HTR6NAMPTLMNA | |
| SCHEMBL16626404 | 0.81 | HTR6 (0.45) | HTR6NAMPTIDEALDH1A1 | |
| SCHEMBL16626785 | 0.81 | HTR6 (0.44) | HTR6NAMPTALDH1A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | claimed |
| CN-105612150-A | Sulfonylindole derivatives and process for producing the same | DAE WOONG PHARMA | 2016-05-25 | — | — | CN | disclosed |