Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LDHB | P07195 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Carbamate SCHEMBL27455257 | 0.89 | — | — | |
| Methyl Carbamate SCHEMBL27839791 | 0.89 | — | — | |
| Methyl Carbamate SCHEMBL788713 | 0.89 | ALDH1A1 (0.50) | ALDH1A1ACHEALOX15LMNABLM | |
| Methyl Carbamate SCHEMBL4140 | 0.89 | — | — | |
| Benzene SCHEMBL27324158 | 0.86 | TSHR (0.43) | LDHALDHBALDH1A1ACHEALOX15 | |
| Methyl Carbamate SCHEMBL27967372 | 0.86 | ACHE (0.50) | LDHALDHBALDH1A1ACHEALOX15 | |
| Methyl Carbamate SCHEMBL50681 | 0.86 | — | — | |
| Methyl Carbamate SCHEMBL3465246 | 0.85 | — | — | |
| Methyl Carbamate SCHEMBL29248750 | 0.85 | — | — | |
| Methyl Carbamate SCHEMBL7127108 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693700-B | Bridged ring compound as hepatitis C inhibitor and preparation method thereof | 广东东阳光药业有限公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-105693700-A | Bridged ring compound as hepatitis C inhibitor and preparation method thereof | 广东东阳光药业有限公司 | 2016-06-22 | — | — | CN | disclosed |