SCHEMBL28068467

SCHEMBL28068467

OCCn1cnc2c(NCc3ccccc3)ncnc21

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMIGD3 P0DMS9 4/20 0.77
ADORA2A P29274 4/20 0.77
ADORA1 P30542 4/20 0.77
RAB9A P51151 2/20 0.72
KMT2A Q03164 1/20 0.72
CDK1 P06493 3/20 0.68
NPC1 O15118 1/20 0.68
HPGD P15428 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
HTT P42858 1/20 0.66
CDK2 P24941 2/20 0.64
CCNB2 O95067 1/20 0.60
CCNB1 P14635 1/20 0.60
CCNB3 Q8WWL7 1/20 0.60
CYP1A2 P05177 1/20 0.59
CTSL P07711 1/20 0.56
ADORA2B P29275 1/20 0.56
TDP1 Q9NUW8 2/20 0.56
HDAC1 Q13547 1/20 0.55
HDAC2 Q92769 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL458946 0.87 TMIGD3 (0.77) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL27734468 0.87 TMIGD3 (1.00) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL29501809 0.86 ADORA3 (0.59) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL17933852 0.85 ADORA2A (0.74) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL22571186 0.84 TMIGD3 (0.81) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL27967736 0.84 RAB9A (0.70) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL17450124 0.81 CDK1 (0.72) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL4382069 0.81 CDK1 (1.00) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL28740202 0.81 RAB9A (0.78) TMIGD3ADORA2AADORA1RAB9AKMT2A
SCHEMBL2049171 0.81 RAB9A (1.00) TMIGD3ADORA2AADORA1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114158570-B Compound agent for reducing stem content of tobacco leaves as well as preparation method and application thereof 四川中烟工业有限责任公司 2022-10-21 CN claimed
CN-114158570-A Compound agent for reducing stem content of tobacco leaves and preparation method and application thereof 四川中烟工业有限责任公司 2022-03-11 CN claimed
CN-104170656-B Grafting method for thin-skin muskmelons 北海市农业科学研究所 2017-02-08 CN claimed
CN-114158570-B Compound agent for reducing stem content of tobacco leaves as well as preparation method and application thereof 四川中烟工业有限责任公司 2022-10-21 CN disclosed
CN-114158570-B Compound agent for reducing stem content of tobacco leaves as well as preparation method and application thereof 四川中烟工业有限责任公司 2022-10-21 CN disclosed
CN-114158570-A Compound agent for reducing stem content of tobacco leaves and preparation method and application thereof 四川中烟工业有限责任公司 2022-03-11 CN disclosed
CN-114158570-A Compound agent for reducing stem content of tobacco leaves and preparation method and application thereof 四川中烟工业有限责任公司 2022-03-11 CN disclosed
CN-105695330-A Screening method for preparing medium-molecular-weight dextran strain 常州市好利莱光电科技有限公司 2016-06-22 CN disclosed