Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27933355 | 0.89 | CCR6 (0.53) | TSHRALDH1A1GAAHPGDNPC1 | |
| SCHEMBL28335604 | 0.89 | ALDH1A1 (0.50) | TSHRALDH1A1GAAHPGDPDE3B | |
| SCHEMBL28333211 | 0.86 | MAPT (0.46) | ALDH1A1GAAHPGDHTTNPC1 | |
| SCHEMBL28068259 | 0.85 | EGFR (0.50) | TSHRALDH1A1GAAHPGDMEN1 | |
| SCHEMBL28335553 | 0.81 | MAPK1 (0.56) | TSHRALDH1A1GAAHPGDNPC1 | |
| SCHEMBL28068265 | 0.80 | ALDH1A1 (0.50) | TSHRALDH1A1GAAHPGDNPC1 | |
| SCHEMBL28333209 | 0.79 | KDM4E (0.57) | TSHRALDH1A1GAAHPGDNPC1 | |
| SCHEMBL10749448 | 0.79 | MAPT (0.61) | TSHRALDH1A1GAAHPGDNPC1 | |
| SCHEMBL28184194 | 0.79 | AKR1C3 (0.59) | TSHRALDH1A1HPGDHTTMEN1 | |
| SCHEMBL28333208 | 0.79 | ALDH1A1 (0.47) | TSHRALDH1A1GAAHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020814-B | Polysubstituted 10-hydroxy phenanthrene and derivative thereof and synthesis method thereof | 南开大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-109020814-A | A kind of polysubstituted 10- hydroxyl is luxuriant and rich with fragrance and its derivative and its synthetic method | 南开大学 | 2018-12-18 | — | — | CN | disclosed |
| CN-105566110-A | Synthesis method of polysubstituted 1-naphthol and derivatives thereof | UNIV NANKAI | 2016-05-11 | — | — | CN | disclosed |