Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269608 | 0.84 | CNR2 (0.43) | CNR2SMN1; SMN2ACP3HPGDLMNA | |
| SCHEMBL8914226 | 0.82 | CNR2 (0.46) | CNR2SMN1; SMN2ACP3HPGDLMNA | |
| SCHEMBL30474559 | 0.81 | CNR2 (0.44) | CNR2SMN1; SMN2ACP3HPGDLMNA | |
| SCHEMBL21659215 | 0.81 | CNR2 (0.44) | CNR2SMN1; SMN2ACP3HPGDLMNA | |
| SCHEMBL8233462 | 0.81 | CNR2 (0.44) | CNR2SMN1; SMN2ACP3HPGDLMNA | |
| SCHEMBL14661312 | 0.80 | HTT (0.46) | SMN1; SMN2LMNAGAAKMT2AHTT | |
| SCHEMBL27985674 | 0.80 | ACP3 (0.50) | CNR2ACP3HPGDLMNAGAA | |
| SCHEMBL28327500 | 0.80 | ACP3 (0.46) | CNR2ACP3LMNAGAAHSD11B1 | |
| SCHEMBL8917002 | 0.79 | ALDH1A1 (0.44) | CNR2SMN1; SMN2ACP3HPGDLMNA | |
| SCHEMBL908987 | 0.79 | CNR2 (0.41) | CNR2SMN1; SMN2ACP3HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687860-B | As P2X7Heterocyclic amide derivatives of receptor antagonists | 埃科特莱茵药品有限公司 | 2016-06-08 | — | — | CN | disclosed |