Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471669 | 0.82 | ACP3 (0.44) | ALDH1A1CNR2SMN1; SMN2ACP3LMNA | |
| SCHEMBL7682991 | 0.82 | ACP3 (0.47) | ALDH1A1CNR2ACP3HPGDLMNA | |
| SCHEMBL8914226 | 0.81 | CNR2 (0.46) | ALDH1A1CNR2SMN1; SMN2ACP3HPGD | |
| SCHEMBL30474559 | 0.79 | CNR2 (0.44) | ALDH1A1CNR2SMN1; SMN2ACP3HPGD | |
| SCHEMBL21659215 | 0.79 | CNR2 (0.44) | ALDH1A1CNR2SMN1; SMN2ACP3HPGD | |
| SCHEMBL8233462 | 0.79 | CNR2 (0.44) | ALDH1A1CNR2SMN1; SMN2ACP3HPGD | |
| SCHEMBL28068541 | 0.79 | CNR2 (0.44) | ALDH1A1CNR2SMN1; SMN2ACP3HPGD | |
| SCHEMBL5457910 | 0.78 | IDO1 (0.44) | ALDH1A1CNR2SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL11176224 | 0.77 | CNR2 (0.36) | CNR2SMN1; SMN2ACP3HPGDKMT2A | |
| SCHEMBL16376975 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2ACP3HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670525-A | Substituted 4-phenyl-6-amino-nicotinic acid compounds useful in the treatment of CNS disorders | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |