Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515890 | 0.81 | LMNA (0.55) | LMNAALDH1A1FAAHMGLLMAPT | |
| SCHEMBL16046615 | 0.77 | TSHR (0.46) | LMNAMAPTSMN1; SMN2HCAR2TSHR | |
| SCHEMBL1088731 | 0.76 | CES1 (0.54) | LMNAALDH1A1FAAHMAPTTSHR | |
| SCHEMBL7642361 | 0.76 | TSHR (0.37) | LMNASMN1; SMN2HCAR2TSHR | |
| SCHEMBL514945 | 0.76 | LMNA (0.61) | LMNAALDH1A1FAAHMGLLMAPT | |
| SCHEMBL4974869 | 0.76 | FAAH (0.57) | LMNAALDH1A1FAAHMAPTABCC4 | |
| SCHEMBL7640159 | 0.75 | LMNA (0.62) | LMNAALDH1A1FAAHMAPT | |
| SCHEMBL7641001 | 0.75 | CA1 (0.41) | LMNATSHR | |
| SCHEMBL3112597 | 0.74 | LMNA (0.65) | LMNAALDH1A1FAAHMGLLMAPT | |
| SCHEMBL3122706 | 0.74 | LMNA (0.65) | LMNAALDH1A1FAAHMGLLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105753834-A | Synthesis method of rosuvastatin calcium key chiral intermediate | 河南师范大学 | 2016-07-13 | — | — | CN | disclosed |