Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13888688 | 0.87 | MAPT (0.42) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL7133160 | 0.84 | MAPT (0.49) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL837451 | 0.84 | ALDH1A1 (0.56) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL15071460 | 0.83 | MAPT (0.49) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL13136740 | 0.83 | MAPT (0.42) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL14035036 | 0.83 | MAPT (0.42) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL4034721 | 0.83 | EGFR (0.55) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10923842 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL2917379 | 0.83 | HTT (0.44) | MAPTALDH1A1HTTMEN1KMT2A | |
| SCHEMBL20521859 | 0.83 | MEN1 (0.47) | MAPTALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103687860-B | As P2X7Heterocyclic amide derivatives of receptor antagonists | 埃科特莱茵药品有限公司 | 2016-06-08 | — | — | CN | disclosed |