SCHEMBL28068668

SCHEMBL28068668

CCOc1ccc(-c2cc[c]c(C(C)C)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.44
ACACB O00763 1/20 0.39
ACACA Q13085 1/20 0.39
PTGS2 P35354 1/20 0.38
ERN1 O75460 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
XDH P47989 1/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
LTA4H P09960 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP7 P09237 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MMP13 P45452 1/20 0.36
MMP14 P50281 1/20 0.36
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10833646 0.76 MCL1 (0.44) ACACBACACANPC1RAB9A
SCHEMBL1370233 0.74 ALDH1A1 (0.36) PTGS2RXRARXRBALDH1A1NPC1
SCHEMBL28981683 0.74 NQO1 (0.61) NQO1ERN1TSHRTDP1XDH
SCHEMBL158260 0.74 NQO1 (0.61) NQO1ERN1TSHRTDP1XDH
SCHEMBL18417193 0.73 NQO1 (0.82) NQO1TSHRTDP1XDHLTA4H
SCHEMBL5833291 0.73 NQO1 (0.82) NQO1TSHRTDP1XDHLTA4H
SCHEMBL9155582 0.73 NQO1 (0.82) NQO1TSHRTDP1XDHLTA4H
SCHEMBL17046255 0.73 NQO1 (0.48) NQO1ACACBACACATSHRTDP1
SCHEMBL2692130 0.72 NQO1 (0.58) NQO1ACACBACACAPTGS2TSHR
SCHEMBL13048467 0.71 NQO1 (0.70) NQO1PTGS2ERN1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102781949-B Phosphinyl amidine compounds, metal complexes, catalyst systems, and their use for oligomerizing or polymerizing olefins 切弗朗菲利浦化学公司 2016-07-06 CN disclosed