Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155582 | 1.00 | NQO1 (0.82) | NQO1TSHRTDP1LTA4HXDH | |
| SCHEMBL18417193 | 1.00 | NQO1 (0.82) | NQO1TSHRTDP1LTA4HXDH | |
| SCHEMBL13048467 | 0.92 | NQO1 (0.70) | NQO1TSHRTDP1LTA4HXDH | |
| 1,4-Diethoxybenzene SCHEMBL124015 | 0.91 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| 1,4-Diethoxybenzene SCHEMBL28186701 | 0.91 | NQO1 (1.00) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL9152440 | 0.90 | LTA4H (0.68) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL12726668 | 0.90 | LTA4H (0.68) | NQO1TSHRTDP1LTA4HKDM4E | |
| SCHEMBL404478 | 0.90 | NQO1 (0.67) | NQO1TSHRTDP1LTA4HXDH | |
| SCHEMBL2492122 | 0.90 | NQO1 (0.67) | NQO1TSHRTDP1LTA4HXDH | |
| SCHEMBL12736285 | 0.90 | NQO1 (0.67) | NQO1TSHRTDP1LTA4HXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117534547-B | Hetero [3] arene macrocyclic compound, and preparation method and application thereof | 东北大学 | 2025-04-08 | — | — | CN | claimed |
| CN-117766187-A | Adsorption method of methyl iodide | 东北大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117534547-A | Hetero [3] arene macrocyclic compound, and preparation method and application thereof | 东北大学 | 2024-02-09 | — | — | CN | claimed |
| CN-115286493-A | Preparation method of 4,4' -diethoxybiphenyl | 北京格林凯默科技有限公司 | 2022-11-04 | — | — | CN | claimed |
| CN-119977743-A | Method for rapidly preparing biphenyl compounds by catalyzing C-C coupling reaction through mechanical grinding method | 辽宁大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-117534547-B | Hetero [3] arene macrocyclic compound, and preparation method and application thereof | 东北大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-117766187-A | Adsorption method of methyl iodide | 东北大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-117534547-A | Hetero [3] arene macrocyclic compound, and preparation method and application thereof | 东北大学 | 2024-02-09 | — | — | CN | disclosed |
| CN-115286493-A | Preparation method of 4,4' -diethoxybiphenyl | 北京格林凯默科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115286493-A | Preparation method of 4,4' -diethoxybiphenyl | 北京格林凯默科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115286493-A | Preparation method of 4,4' -diethoxybiphenyl | 北京格林凯默科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
| US-10578774-B2 | Retardation-increasing agent, cellulose-based resin composition using same, and film | ADEKA CORPORATION (JP) | 2020-03-03 | — | — | US | disclosed |
| US-6964967-B2 | Substituted pyrido[2,3-d]pyrimidines and methods for their use | AMGEN, INC. (US) | 2005-11-15 | — | — | US | disclosed |
| US-20050075333-A1 | CXCR3 antagonists | TULARIK INC. | 2005-04-07 | — | — | US | disclosed |
| US-6794379-B2 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE; SKIN DISORDERS | TULARIK INC. | 2004-09-21 | — | — | US | disclosed |
| EP-1343505-A1 | CXCR3 ANTAGONISTS | Tularik Inc. (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20030069234-A1 | CXCR3 antagonists | AMGEN INC. | 2003-04-10 | — | — | US | disclosed |
| US-20030055054-A1 | CXCR3 antagonists | TULARIK, INC. | 2003-03-20 | — | — | US | disclosed |
| US-20020169159-A1 | An acetamide derivative is useful for treatment of inflammatory and immune conditions and diseases; modulates the expressin and/or function of a chemokine receptor | TULARIK INC. (US) | 2002-11-14 | — | — | US | disclosed |
| WO-2002083143-A1 | CXCR3 ANTAGONISTS | TULARIK INC. (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075333-A1 | CXCR3 antagonists | CXCR3, CXCR1, CCR5 | NQO1 3414/4885TSHR 975/4885TDP1 3854/4885 |
| US-20030069234-A1 | CXCR3 antagonists | CXCR3, CXCR1, CCR5 | NQO1 3414/4885TSHR 975/4885TDP1 3854/4885 |
| US-20020169159-A1 | An acetamide derivative is useful for treatment of inflammatory and immune conditions and diseases; modulates the expressin and/or function of a chemokine receptor | CCR2, CCR1, ACKR3 | NQO1 2997/4885TSHR 1129/4885TDP1 4230/4885 |
| US-20030055054-A1 | CXCR3 antagonists | CXCR3, CXCR1, CCR5 | NQO1 3414/4885TSHR 975/4885TDP1 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.