Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.38 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.38 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28392614 | 0.83 | AKT1 (0.36) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL5704757 | 0.81 | — | — | |
| SCHEMBL5704755 | 0.81 | — | — | |
| SCHEMBL3423749 | 0.78 | MAPT (0.41) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL11364536 | 0.78 | SMN1; SMN2 (0.46) | MAPTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL4896000 | 0.77 | MAPT (0.44) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL6470886 | 0.77 | MAPT (0.40) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL6259567 | 0.77 | RECQL (0.41) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL6259565 | 0.77 | RECQL (0.41) | MAPTLMNARECQLPLIN1PLIN5 | |
| SCHEMBL3697930 | 0.77 | ALDH1A1 (0.42) | MAPTLMNARECQLPLIN1PLIN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833540-B | A kind of beta substitution cinnamophenone analogue and its preparation method and the application in preparation NSC 630176 | 中山大学 | 2016-06-08 | — | — | CN | disclosed |