Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | BCHE | P06276 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.53 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068734 | 1.00 | MAPT (0.54) | MAPTRAB9ANPC1BCHELMNA | |
| SCHEMBL3183044 | 0.85 | MAPT (0.55) | MAPTRAB9ANPC1BCHELMNA | |
| SCHEMBL7559547 | 0.85 | RAB9A (0.59) | MAPTRAB9ANPC1BCHELMNA | |
| SCHEMBL3183029 | 0.85 | MAPT (0.55) | MAPTRAB9ANPC1BCHELMNA | |
| SCHEMBL7559553 | 0.85 | RAB9A (0.59) | MAPTRAB9ANPC1BCHELMNA | |
| SCHEMBL8105301 | 0.84 | PTGER3 (0.61) | MAPTNFKB1SMN1; SMN2KDM4E | |
| SCHEMBL8105303 | 0.84 | PTGER3 (0.61) | MAPTNFKB1SMN1; SMN2KDM4E | |
| SCHEMBL28331101 | 0.83 | MAPT (0.54) | MAPTRAB9ANPC1BCHELMNA | |
| SCHEMBL28314097 | 0.83 | MAPT (0.54) | MAPTRAB9ANPC1BCHELMNA | |
| SCHEMBL28288349 | 0.82 | PTGER3 (0.56) | MAPTRAB9ANPC1BCHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103833540-B | A kind of beta substitution cinnamophenone analogue and its preparation method and the application in preparation NSC 630176 | 中山大学 | 2016-06-08 | — | — | CN | disclosed |