Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24742783 | 0.85 | POLB (0.47) | ALDH1A1SMN1; SMN2PRF1 | |
| SCHEMBL30420588 | 0.84 | GRM5 (0.51) | KDM4EALDH1A1HSD17B10BRD4BRPF1 | |
| SCHEMBL5576465 | 0.81 | CASP3 (0.51) | KDM4EALDH1A1HSD17B10BRD4SMN1; SMN2 | |
| SCHEMBL30957893 | 0.81 | CASP3 (0.51) | KDM4EALDH1A1HSD17B10BRD4SMN1; SMN2 | |
| SCHEMBL29606190 | 0.77 | PIK3CA (0.50) | PARP1KDM4EALDH1A1HSD17B10BRD4 | |
| SCHEMBL29552307 | 0.76 | CASP1 (0.47) | PARP1KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL2144936 | 0.76 | CASP1 (0.47) | PARP1KDM4EALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL25317766 | 0.76 | CRBN (0.47) | UGCG | |
| SCHEMBL31098598 | 0.76 | CRBN (0.47) | UGCG | |
| SCHEMBL435022 | 0.74 | METAP1 (0.44) | HSD17B10PARP10NPC1RAB9APRF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103797000-B | Amidine compound or salt thereof | 大正制药株式会社 | 2016-07-06 | — | — | CN | disclosed |