Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27577885 | 0.92 | ALDH1A1 (0.41) | ALDH1A1TP53LMNAMAPK1 | |
| SCHEMBL107616 | 0.92 | — | — | |
| Acetic Acid SCHEMBL28136110 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TP53LMNAMAPK1 | |
| SCHEMBL27572585 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL27484358 | 0.90 | — | — | |
| Methane SCHEMBL28312214 | 0.90 | — | — | |
| Nitric Acid SCHEMBL5696204 | 0.87 | CA5A (0.42) | ALDH1A1TP53LMNAMAPK1 | |
| Potassium Ion SCHEMBL28442945 | 0.87 | ALDH1A1 (0.39) | ALDH1A1TP53LMNAMAPK1 | |
| Ethylene SCHEMBL7111339 | 0.87 | — | — | |
| Methylamine SCHEMBL28188163 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105762366-A | Composite current collector of lithium ion battery and manufacturing method of composite current collector | 江苏深苏电子科技有限公司 | 2016-07-13 | — | — | CN | disclosed |