Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29047738 | 0.87 | KLK7 (0.46) | LMNACYP2D6SMN1; SMN2CYP1A2PKM | |
| SCHEMBL28650264 | 0.85 | KLK7 (0.45) | LMNACYP2D6SMN1; SMN2CYP1A2PKM | |
| SCHEMBL28014617 | 0.79 | LMNA (0.48) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL29047733 | 0.79 | MTNR1A (0.40) | MAPK1KMT2AALDH1A1TDP1 | |
| SCHEMBL6553756 | 0.78 | LMNA (0.47) | LMNAMAPK1CES2CES1NAAA | |
| SCHEMBL29214557 | 0.78 | MTNR1A (0.39) | MAPK1KMT2AALDH1A1TDP1 | |
| SCHEMBL1275430 | 0.77 | LMNA (0.54) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL8876742 | 0.77 | LMNA (0.54) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL27817331 | 0.76 | HPGD (0.49) | LMNAMAPK1CES2CES1CYP2D6 | |
| SCHEMBL27888601 | 0.75 | LMNA (0.52) | LMNAMAPK1CES2CES1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435735-B2 | Methods and compounds for detection of molecular targets | DAKO DENMARK A/S (DK) | 2013-05-07 | — | — | US | disclosed |
| US-20100240047-A1 | METHODS AND COMPOUNDS FOR DETECTION OF MOLECULAR TARGETS | DAKO DENMARK APS (DK) | 2010-09-23 | — | — | US | disclosed |