Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 19/20 | 0.64 |
| ▸ | CHRM3 known ✓ | P20309 | 16/20 | 0.64 |
| ▸ | CHRM1 known ✓ | P11229 | 12/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 15/20 | 0.64 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL42703 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL10723477 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL286149 | 0.97 | CHRM2 (0.67) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL9749642 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL28069006 | 0.94 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Water SCHEMBL8028259 | 0.94 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL286148 | 0.94 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| SCHEMBL33571 | 0.94 | — | — | |
| Methyl Alcohol SCHEMBL10541004 | 0.92 | CHRM2 (0.61) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL27283131 | 0.92 | CHRM2 (0.61) | CHRM2CHRM3CHRM5CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105658043-B | A kind of electromagnetic shielding membrane material and preparation method thereof | 东华大学 | 2018-09-18 | — | — | CN | claimed |
| CN-105658043-A | Electromagnetic shielding film material and preparation method thereof | 东华大学 | 2016-06-08 | — | — | CN | claimed |
| CN-105658043-A | Electromagnetic shielding film material and preparation method thereof | 东华大学 | 2016-06-08 | — | — | CN | disclosed |