Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 19/20 | 0.67 |
| ▸ | CHRM3 known ✓ | P20309 | 16/20 | 0.67 |
| ▸ | CHRM1 known ✓ | P11229 | 12/20 | 0.62 |
| ▸ | CHRM5 | P08912 | 15/20 | 0.67 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9749642 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL42703 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL10723477 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28069007 | 0.97 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Hydrochloric Acid SCHEMBL286148 | 0.97 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Water SCHEMBL8028259 | 0.97 | CHRM2 (0.64) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| SCHEMBL33571 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL27283131 | 0.95 | CHRM2 (0.61) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Methyl Alcohol SCHEMBL10541004 | 0.95 | CHRM2 (0.61) | CHRM2CHRM3CHRM5CHRM4CHRM1 | |
| Ethylene SCHEMBL29049658 | 0.95 | CHRM2 (0.61) | CHRM2CHRM3CHRM5CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107384363-A | Salt tolerant is from suspended prop | 自悬浮支撑有限公司 | 2017-11-24 | — | — | CN | disclosed |
| EP-2616585-B1 | MODIFIED CELLULOSE FIBRES | SÖDRA SKOGSÄGARNA EKONOMISKA FÖRENING (SE) | 2014-07-23 | — | — | EP | disclosed |
| EP-2616585-A1 | MODIFIED CELLULOSE FIBRES | Södra Skogsägarna Ekonomiska Förening (SE) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034997-A1 | MODIFIED CELLULOSE FIBRES | SÖDRA SKOGSÄGARNA EKONOMISK FÖRENING (SE) | 2012-03-22 | — | — | WO | disclosed |
| EP-2428610-A1 | Modified cellulose fibres | Södra Skogsägarna ekonomisk förening (SE) | 2012-03-14 | — | — | EP | disclosed |
| EP-0570532-B1 | QUATERNIZED PANTHENOL COMPOUNDS AND THEIR USE | SMITH RONALD J (US) | 1996-08-28 | — | — | EP | disclosed |
| US-5136093-A | Cosmetic products | INNOVACHEM, LLC | 1992-08-04 | — | — | US | disclosed |