Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | IAPP | P10997 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668620 | 0.81 | ESR1 (0.48) | KMT2AMEN1ALOX5IAPPPOLB | |
| SCHEMBL6678566 | 0.81 | ESR1 (0.48) | KMT2AMEN1ALOX5IAPPPOLB | |
| SCHEMBL6063979 | 0.81 | TYR (0.55) | MAOBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL17691455 | 0.79 | MAOB (0.50) | MAOBKMT2AMEN1ALOX5HTR1A | |
| SCHEMBL29009291 | 0.78 | HTR1A (0.48) | MAOBKMT2AMEN1ALOX5HTR1A | |
| SCHEMBL27707848 | 0.75 | APP (0.60) | — | |
| SCHEMBL11827772 | 0.75 | NFKB1 (0.65) | MAOBKMT2AMEN1ALOX5HTR1A | |
| SCHEMBL11827763 | 0.75 | NFKB1 (0.65) | MAOBKMT2AMEN1ALOX5HTR1A | |
| SCHEMBL29154472 | 0.74 | HPGD (0.54) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL11827066 | 0.72 | POLB (0.58) | MAOBKMT2AMEN1ALOX5IAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622884-A | Organic foam thermal-insulation building material and preparation method thereof | SUZHOU FUZHONG PLASTIC CO LTD | 2016-06-01 | — | — | CN | disclosed |