Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | UBE2N | P61088 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 3/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | MDH1 | P40925 | 4/20 | 0.34 |
| ▸ | MDH2 | P40926 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084286 | 0.83 | SHBG (0.40) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL28901114 | 0.77 | CYP3A4 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1SHBG | |
| SCHEMBL28308871 | 0.77 | CA1 (0.39) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 | |
| Phosphoric Acid SCHEMBL28069041 | 0.76 | SHBG (0.41) | SMN1; SMN2MAPK1MEN1KMT2ASHBG | |
| SCHEMBL6739022 | 0.75 | CA1 (0.40) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL7456553 | 0.75 | SHBG (0.40) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL10809182 | 0.75 | SHBG (0.40) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL3150998 | 0.74 | SHBG (0.42) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 | |
| Lithium Ion SCHEMBL21541943 | 0.74 | CA1 (0.39) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL28468987 | 0.74 | CA1 (0.39) | SMN1; SMN2MAPK1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104448541-B | Polypropylene composition and polypropylene material | 中国石油化工股份有限公司 | 2017-02-01 | — | — | CN | disclosed |
| CN-104250397-B | A kind of polypropene composition and polypropylene knotting packaging film | 中国石油化工股份有限公司 | 2016-12-28 | — | — | CN | disclosed |
| CN-105623078-A | Polymer membrane and preparation method thereof | CHINA PETROLEUM & CHEM CORP | 2016-06-01 | — | — | CN | disclosed |
| CN-105623074-A | Non-woven fabric raw material and preparation method thereof, and preparation method of non-woven fabric | CHINA PETROLEUM & CHEM CORP | 2016-06-01 | — | — | CN | disclosed |