Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 3/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28829370 | 0.88 | KDM1A (0.38) | MERTKDDB1CRBNDRD2KDM1A | |
| Tert-Butyl Formate SCHEMBL27940168 | 0.86 | MERTK (0.35) | MERTKAXLBRD4SYKDRD2 | |
| SCHEMBL9941953 | 0.74 | PKM (0.48) | DDB1CRBNLMNA | |
| SCHEMBL9941478 | 0.74 | MERTK (0.39) | MERTKAXLBRD4SYKDRD2 | |
| SCHEMBL27921618 | 0.74 | DDB1 (0.37) | BRD4DDB1CRBNLMNA | |
| SCHEMBL9941587 | 0.73 | DDB1 (0.44) | DDB1CRBN | |
| SCHEMBL15312561 | 0.72 | FEN1 (0.47) | HTR6KDM1A | |
| SCHEMBL15312469 | 0.72 | FEN1 (0.47) | HTR6KDM1A | |
| SCHEMBL15312555 | 0.71 | KDM4E (0.47) | MERTKHTR6 | |
| SCHEMBL3537839 | 0.70 | DDB1 (0.41) | MERTKDDB1CRBNDRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103347882-B | Substituted N- (1H-indazol-4-yl) imidazo [1,2-a ] pyridine-3-carboxamide compounds as type III receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2016-05-11 | — | — | CN | disclosed |