Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | FABP6 | P51161 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23352486 | 0.81 | CXCR4 (0.42) | MEN1MAPK10GFERKMT2ANPC1 | |
| SCHEMBL10405315 | 0.79 | MEN1 (0.61) | MEN1MAPK10GFERKMT2ANPC1 | |
| SCHEMBL28069466 | 0.79 | KDM4E (0.47) | MEN1MAPK10GFERKMT2ANPC1 | |
| SCHEMBL7448182 | 0.78 | MEN1 (0.50) | MEN1MAPK10GFERKMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL8742967 | 0.77 | MEN1 (0.58) | MEN1MAPK10GFERKMT2ANPC1 | |
| SCHEMBL28279163 | 0.77 | MEN1 (0.48) | MEN1MAPK10GFERKMT2ANPC1 | |
| SCHEMBL2227737 | 0.76 | — | — | |
| SCHEMBL19581189 | 0.72 | MEN1 (0.48) | MEN1MAPK10GFERKMT2ANPC1 | |
| SCHEMBL28591049 | 0.72 | GAA (0.62) | GFERKMT2ANPC1RAB9APKM | |
| SCHEMBL7018736 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080194545-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | TRIUS THERAPEUTICS (US) | 2008-08-14 | — | — | US | disclosed |
| US-20080194545-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | TRIUS THERAPEUTICS (US) | 2008-08-14 | — | — | US | disclosed |
| WO-2003035070-A1 | ANTIHISTAMINIC/ANTITUSSIVE COMPOSITIONS | MEDPOINTE HEALTHCARE, INC. (US) | 2003-05-01 | — | — | WO | disclosed |
| US-20030083354-A1 | Phenylephrine tannate and pyrilamine tannate salts in pharmaceutical compositions | PEDIAMED PHARMACEUTICALS, INC. | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194545-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | ABCB11, FPR1, C5 | MEN1 1366/4885MAPK10 4133/4885GFER 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.