Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23001613 | 0.77 | CYP2D6 (0.39) | CTSKPTPRCCYP2D6HDAC3HDAC1 | |
| SCHEMBL19287255 | 0.76 | ATM (0.47) | CTSKCTSS | |
| SCHEMBL22769358 | 0.76 | CYP1A2 (0.39) | CTSKPTPRCCYP2D6 | |
| SCHEMBL763067 | 0.75 | CA12 (0.38) | CTSKPTPRCCYP2D6CTSSCA12 | |
| SCHEMBL374867 | 0.75 | CTSK (0.66) | CTSKCTSSCA2 | |
| SCHEMBL1802737 | 0.75 | CTSK (0.66) | CTSKCTSSCA2 | |
| SCHEMBL12538274 | 0.75 | CTSK (0.66) | CTSKCTSSCA2 | |
| SCHEMBL1162877 | 0.74 | CTSK (0.42) | CTSKPTPRCCYP2D6HDAC3HDAC1 | |
| SCHEMBL4971083 | 0.74 | CTSK (0.42) | CTSKPTPRCCYP2D6HDAC3HDAC1 | |
| SCHEMBL4096308 | 0.74 | CTSK (0.42) | CTSKPTPRCCYP2D6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585583-A | Non-peptide IAP (inhibitor of apoptosis protein) antagonist as well as synthetic method and application thereof | UNIV GUANGDONG TECHNOLOGY | 2016-05-18 | — | — | CN | claimed |
| CN-105585583-B | A kind of non-peptides apoptosis inhibitory protein antagonist and its synthetic method and application | 广东工业大学 | 2018-04-13 | — | — | CN | disclosed |
| CN-105585583-A | Non-peptide IAP (inhibitor of apoptosis protein) antagonist as well as synthetic method and application thereof | UNIV GUANGDONG TECHNOLOGY | 2016-05-18 | — | — | CN | disclosed |